Can I Take alpha lipoic acid and metformin Together?

SUMMARY:

Alpha‑lipoic acid can modestly enhance glucose‑lowering effects, so taking it with metformin carries a small increased risk of low blood sugar; monitoring of blood glucose and symptoms is recommended.

ADDITIONAL NOTES:

Alpha‑lipoic acid is a supplement that can improve insulin sensitivity and lower blood glucose; metformin is an antihyperglycemic (biguanide). The interaction is minor but may increase risk of hypoglycemia—although metformin alone rarely causes hypoglycemia, additive effects can occur. Monitor fasting and postprandial glucose, watch for hypoglycemia symptoms (sweating, shakiness, dizziness, confusion), and inform your prescriber; dose adjustments or closer monitoring may be appropriate for elderly patients or those with renal impairment.