SUMMARY:
Oral iron and calcium reduce iron absorption when taken together, which can lower iron’s effectiveness; spacing doses apart (commonly about 2 hours) or taking iron with vitamin C can help. This combination is generally used with caution rather than avoided entirely, especially when treating iron deficiency.
ADDITIONAL NOTES:
Mechanism: calcium can bind to oral iron or compete for absorption in the gut, decreasing iron bioavailability. Timing: separate doses when possible (commonly ≥2 hours between iron and calcium-containing supplements, dairy, or antacids). Clinical significance: reduced iron absorption may impair treatment of iron-deficiency anemia if taken together chronically. Other considerations: taking iron with vitamin C (ascorbic acid) or on an empty stomach can improve absorption, but iron may cause GI upset; discuss monitoring (e.g., hemoglobin/ferritin) with your clinician if on long-term therapy.
MEDICAL DISCLAIMER
This information is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before making any changes to your supplement or medication regimen. Drug interactions can vary based on individual health conditions, dosages, and other factors.
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