Drug Interaction - CanITakeThis.com

Can I Take melatonin and diphenhydramine Together?

STATUS: CAUTION

SUMMARY:

Using melatonin together with diphenhydramine may increase central nervous system side effects such as dizziness, drowsiness, confusion, and difficulty concentrating.

ADDITIONAL NOTES:

The combination can enhance CNS depression, leading to greater drowsiness and impaired coordination. Common precautions include avoiding driving or operating machinery until you know how they affect you, and limiting alcohol or other sedatives. Consider medical advice if you are elderly, have glaucoma or urinary retention, or are taking other sedating medications.

MEDICAL DISCLAIMER

This information is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before making any changes to your supplement or medication regimen. Drug interactions can vary based on individual health conditions, dosages, and other factors.

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