SUMMARY:
Combining melatonin with Tylenol PM (which contains diphenhydramine) may increase sedative effects such as drowsiness and dizziness; use with caution.
ADDITIONAL NOTES:
Diphenhydramine (an antihistamine in Tylenol PM) can cause drowsiness and impair cognitive or motor function. When taken with melatonin, these sedative effects may be additive, leading to increased dizziness, drowsiness, confusion, or impaired concentration. This combination is not automatically unsafe, but caution is advised, especially for activities requiring alertness or in older adults.
MEDICAL DISCLAIMER
This information is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before making any changes to your supplement or medication regimen. Drug interactions can vary based on individual health conditions, dosages, and other factors.
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