Can I Take melatonin and zzzquil Together?

SUMMARY:

Taking melatonin together with ZzzQuil (diphenhydramine) can increase drowsiness and sedation; use caution and avoid activities requiring alertness until you know how the combination affects you.

ADDITIONAL NOTES:

- Both products can cause sedation; when used together their effects are additive, increasing sleepiness and impaired coordination. - ZzzQuil (diphenhydramine) also has anticholinergic effects (dry mouth, blurred vision, constipation, urinary retention) and may increase confusion or fall risk, especially in older adults. - Avoid alcohol or other central nervous system depressants while combining these agents. - If you have sleep apnea, severe respiratory disease, are elderly, pregnant, nursing, or take other sedating medications, consult a healthcare professional before combining them. - If you experience excessive drowsiness, confusion, difficulty breathing, or other concerning symptoms, seek medical advice promptly.