Can I Take vitamin d and vitamin k2 Together?

SUMMARY:

Vitamin D and vitamin K2 are generally compatible and are often taken together to support bone health; K2 helps direct calcium into bone and may counteract vascular calcium deposition that can be promoted by higher vitamin D–driven calcium absorption. For most people on typical supplement doses this combination is considered safe, but individual factors (especially use of blood thinners) can change risk.

ADDITIONAL NOTES:

- Mechanism: Vitamin D increases intestinal calcium absorption; vitamin K2 activates proteins (osteocalcin, matrix Gla protein) that help bind calcium into bone and inhibit arterial calcification. - Typical risk: No direct harmful interaction for most people at usual supplement doses. - Important caution: Vitamin K (including K2) can reduce the effectiveness of vitamin K–antagonist anticoagulants (e.g., warfarin); if you are on anticoagulation, consult your prescriber before starting K2. - High-dose supplements: If taking very high doses of vitamin D or K2, monitor calcium levels and follow medical advice. - If you have conditions affecting calcium metabolism (e.g., hypercalcemia, severe kidney disease), seek medical guidance before combining supplements.