SUMMARY:
These products contain the same active ingredient (acetaminophen), so taking them together risks exceeding the recommended daily acetaminophen dose and causing liver injury; avoid combining unless you account for total acetaminophen from all sources. Other ingredients (doxylamine, dextromethorphan) do not add a major interaction with acetaminophen but check for sedation or other effects from multi-ingredient products.
ADDITIONAL NOTES:
Primary concern is duplicate acetaminophen exposure and potential hepatotoxicity if the combined acetaminophen dose exceeds recommended limits; check product labels for acetaminophen milligrams per dose and total daily intake (typical maximum is 3–4 g/day depending on guidance), avoid in severe liver disease or with regular heavy alcohol use, and seek medical/pharmacy advice for safe dosing. Doxylamine (sedating antihistamine) and dextromethorphan (cough suppressant) generally do not interact significantly with acetaminophen but may cause sedation or other side effects when taken with other sedating medications.
MEDICAL DISCLAIMER
This information is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before making any changes to your supplement or medication regimen. Drug interactions can vary based on individual health conditions, dosages, and other factors.
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