SUMMARY:
There is no well-established clinically significant interaction between vitamin B12 (cyanocobalamin) and caffeine; they are generally considered safe to take together for most people.
ADDITIONAL NOTES:
No major pharmacologic interaction is reported. Caffeine does not directly alter the clinical effects of injectable or oral B12 at typical doses. Some observational studies around dietary coffee consumption suggest high intake might reduce vitamin B12 absorption from food in susceptible individuals, but this does not imply a direct drug–drug interaction. Monitor for expected effects (e.g., caffeine-related jitteriness, insomnia) and address any concerns about nutrient absorption with a healthcare provider.
MEDICAL DISCLAIMER
This information is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before making any changes to your supplement or medication regimen. Drug interactions can vary based on individual health conditions, dosages, and other factors.
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