Can I Take coq10 with statins?

SUMMARY:

CoQ10 supplements and statin medications are generally compatible for most people; statins can lower the body’s CoQ10 levels and some patients take CoQ10 to try to reduce statin-associated muscle symptoms. There is no well-established harmful pharmacologic interaction, but monitor for persistent muscle pain or other adverse effects and discuss with your clinician.

ADDITIONAL NOTES:

CoQ10 is a dietary supplement (coenzyme Q10) and statins are HMG-CoA reductase inhibitors. Statins commonly reduce endogenous CoQ10 concentrations; supplementing CoQ10 is often used empirically for statin-associated myalgia, although trial results are mixed. CoQ10 does not have a major effect on statin metabolism and is not known to reduce statin efficacy. Watch for new or worsening muscle pain, weakness, dark urine, or signs of liver injury; report these to your healthcare provider. As with any supplement or medication change, consult your prescriber or pharmacist for personalized advice and to check for other drug interactions.