Can I Take creatine with protein powder?

SUMMARY:

Combining creatine and protein powder is generally considered likely safe for healthy adults when taken at recommended doses; however, people with kidney disease, those taking nephrotoxic medications, or who become dehydrated should use caution and consult a clinician.

ADDITIONAL NOTES:

Both are dietary supplements commonly used together to support muscle growth and performance. Primary concerns are in people with preexisting kidney impairment or taking nephrotoxic drugs — creatine can raise serum creatinine (affecting lab interpretation) and high protein intake plus creatine may increase renal workload or dehydration risk. Recommend staying well hydrated, following dosing instructions, and checking kidney function with a healthcare provider if you have risk factors or symptoms (reduced urine output, swelling, unexplained fatigue).