Can I Take guiafenesis with ibuprofen?

SUMMARY:

These two medications are generally considered likely safe to use together for most people, with no major drug–drug interaction expected. Monitor for side effects such as stomach upset, nausea, or dizziness and consult a clinician if you have concerns or underlying conditions.

ADDITIONAL NOTES:

Guaifenesin is an expectorant and ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID); they act by different mechanisms and have no major pharmacologic interaction. Possible additive adverse effects to watch for include gastrointestinal upset from ibuprofen and occasional nausea or dizziness from guaifenesin. Use caution with ibuprofen if you have kidney disease, peptic ulcer disease, or take anticoagulants—those conditions raise risk independent of guaifenesin. If you experience severe side effects or allergic reactions, stop the drugs and seek medical care.