SUMMARY:
No direct interactions were identified between melatonin and L-theanine; together they are often used to promote relaxation and sleep. They may produce additive drowsiness in some people, so caution is advised with activities requiring alertness or when combined with other sedatives.
ADDITIONAL NOTES:
Melatonin is a hormone/supplement used to regulate sleep; L-theanine is an amino acid that can promote relaxation. The main concern is additive sedative effects (increased sleepiness, impaired alertness). Use caution if you take other central nervous system depressants (benzodiazepines, opioids, alcohol) or have conditions where increased sedation is risky. Individual responses vary; older adults and pregnant or breastfeeding people should consult a clinician. Absence of reported interactions does not guarantee safety for every person or situation.
MEDICAL DISCLAIMER
This information is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before making any changes to your supplement or medication regimen. Drug interactions can vary based on individual health conditions, dosages, and other factors.
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