Can I Take vitamin k with warfarin?

SUMMARY:

Vitamin K reduces the anticoagulant effect of warfarin, which can lower INR and increase the risk of blood clots if vitamin K intake rises or becomes inconsistent. This is a moderate interaction typically managed by keeping vitamin K intake consistent and monitoring INR closely.

ADDITIONAL NOTES:

Vitamin K is the physiological cofactor for activation of clotting factors; warfarin inhibits vitamin K recycling. Increased vitamin K (from supplements or diet) can antagonize warfarin and decrease INR/anticoagulation. Sudden changes in vitamin K intake can destabilize warfarin control. Management commonly includes maintaining a consistent dietary/supplement intake of vitamin K, more frequent INR monitoring, and possible warfarin dose adjustment by a clinician. Watch for signs of reduced anticoagulation (new or worsening swelling, pain in limbs, chest pain, shortness of breath) and report changes to a healthcare provider.